Probably the fastest I/RPC implementation for Python should be
OmniOrbpy:

http://omniorb.sourceforge.net/

It's cross-platform, language-independent and standard-(Corba-)
compliant.
I don't want to use IDL though. Clients will be written in Python, and it would be a waste of time to write IDL files.

I have seen a stand alone cross platform IPC server before that could
serve "channels", and send/receive messages using these channels. But
I don't remember its name and now I cannot find it. Can somebody
please help?
If it's just for "messaging", Spread should be interesting:

http://www.spread.org/

Also cross-platform & language-independent.
Looks promising. This is what I have found about it:

http://stackoverflow.com/questions/35490/spread-vs-mpi-vs-zeromq


So, it really depends on whether you are trying to build a parallel system or distributed system. They are related to each other, but the implied connotations/goals are different. Parallel programming deals with increasing computational power by using multiple computers simultaneously. Distributed programming deals with reliable (consistent, fault-tolerant and highly available) group of computers.

I don't know the full theory behind distributed programming or parallel programming. ZMQ seems easier to use.



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