I just came across this (https://gist.github.com/1208215):

    import sys
    import ctypes
    pyint_p = ctypes.POINTER(ctypes.c_byte*sys.getsizeof(5))
    five = ctypes.cast(id(5), pyint_p)
    print(2 + 2 == 5) # False
    five.contents[five.contents[:].index(5)] = 4
    print(2 + 2 == 5) # True (must be sufficiently large values of 2 there...)

Heh.  The author is apparently anonymous, I guess for good reason.
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