It is probably the best to calculate back to UTC. Assume "2005-06-07 15:07:12" the local time, then convert it as follows to UTC. Use the UTC time to store/manipulate/whatever you want to do.
import time
t = time.mktime(time.strptime("2005-06-07 15:07:12", "%Y-%m-%d
%H:%M:%S"))
print time.ctime(t)
offset = time.timezone
if time.daylight:
offset = time.altzone
t += offset
print time.ctime(t)
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