Maybe something like this will work though I am not sure of my quotes and what to import
import shutil
f = open(r'C:\Users\Owner\Desktop\mydata.txt', 'r')
read_data1 = f.read()
f.close()
shutil.copy('C:\Users\Owner\Desktop\newdata.txt', 'C:\Users\Owner
\Desktop\out.txt')
file = open(r'C:\Users\Owner\Desktop\out.txt', 'w')
file.write(text.replace(read_data1, ""))
file.close()
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