I've been working on a python based tool named autoglade that could be of help to simplify application development using glade as the interface designer. There is a lot of room for improvement but it's pretty usable right now.
You can download autoglade from http://sourceforge.net/projects/autoglade. A basic tutorial can be found in the wiki: http://autoglade.wiki.sourceforge.net/autoglade+tutorial+-+first+steps This tutorial shows how you can create "applications" only from the glade definition, no programming. A great companion for tools like nautilus actions. Comments, suggestions, critics, bugs, fixes, etc are gladly welcome. -- Diego Torres Milano -- http://mail.python.org/mailman/listinfo/python-list
