What I'm getting at is that it looks like one of these arch flags needs to be removed, as a previous poster said. I remember having a similar issue with an arch flag when installing some Python module (don't remember whether it was MySQLdb or not), and I fixed it by installing the Universal SDK that comes with XCode on OS 10.4. If this is not an option for you (and it sounds as though it may not be), you might also try editing the Makefile to remove the flag corresponding to the architecture that does not match your system.
"uname -a" should tell you which architecture you're on as well as what version of the OS you're running. -- http://mail.python.org/mailman/listinfo/python-list
