Christoph Gohlke added the comment:

FWIW, I rebuilt static libraries for zlib, jbig, jpeg, openjpeg, tiff, webp, 
lcms, and freetype with /MT flag (a tedious task) and was able to build 
matplotlib and Pillow using Python 3.5.0rc1. As expected there is no dependency 
on the vcruntime DLL.

Even if everything is built with /MT and using UCRT, some extensions will still 
depend on version specific Visual C runtime DLLs, e.g. OpenMP, requiring users 
or distributors to install/bundle the VC runtime package.

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Python tracker <rep...@bugs.python.org>
<http://bugs.python.org/issue24872>
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