Thomas Kluyver added the comment:

I think there's an issue with this change - ismethoddescriptor() doesn't 
guarantee that that the object has an __objclass__ attribute. Unbound PyQt4 
signals appear to be a case where this goes wrong.

This came up testing IPython on Python 3.4 - we subclass DocTestFinder, which 
creates other problems, but it looks like it would run into trouble even with 
the base implementation.
https://github.com/ipython/ipython/issues/4892

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nosy: +takluyver

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