Hi Marc,

The latest versions of PyMOL (e.g. 2.4) work fine on macOS Big Sur.
Old versions of MacPyMOL (until 1.8.6) are not compatible, unfortunately,
and we're not aware of any workarounds to make it work. Upgrading PyMOL is
your only option.

Cheers,
  Thomas


On Mon, Apr 19, 2021 at 8:16 AM Marc Graille <marc.grai...@polytechnique.edu>
wrote:

> Hello,
>
> I have recently updated the iOS of my MacBook Air to Big Sur (version
> 11.2.3) and since then, I cannot use Pymol anymore. This is very annoying
> as it is my favorite program to generate publication grade figures.
>
> Here is the error message I get :
> *This Executable Build integrates and extends Open-Source PyMOL 1.7.2.3.*
> * Detected OpenGL version 2.0 or greater. Shaders available.*
> * Detected GLSL version 1.20.*
> * Detected 8 CPU cores.  Enabled multithreaded rendering.*
> * OpenGL graphics engine:*
> *  GL_VENDOR:   Intel Inc.*
> *  GL_RENDERER: Intel(R) Iris(TM) Plus Graphics OpenGL Engine*
> *  GL_VERSION:  2.1 INTEL-16.1.12*
> *ERROR: CGOOptimizeScreenTexturesAndPolygons() glGenBuffers returns
> err=1281*
>
> My graphics card is : Intel Iris Plus Graphics 1536 Mo.
>
> Any solution to solve this problem?
>
> Thanks a lot for your help,
>
> Yours,
>
> Marc
>
>
> —
> *Marc GRAILLE, PhD*
> DR1-CNRS
> Laboratoire de Biologie Structurale de la Cellule  (BIOC; Ex-Laboratoire
> de Biochimie)
> UMR7654 du CNRS
>
> Head of the team: “Translation and degradation of eukaryotic mRNAs”
>
> *ÉCOLE POLYTECHNIQUE*
> 91128 PALAISEAU CEDEX
> FRANCE
> 📞: +33 (0)1 69 33 48 90
>
>  : marc.grai...@polytechnique.edu / : @GrailleLab
> <https://twitter.com/GrailleLab>
>
> https://portail.polytechnique.edu/bioc/en/research/coupling-between-translation-and-mrna-degradation-eukaryotes
> —
>
>
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