Thanks for your comments, Benny.
The file was a bad mix of old configuration remnants :\
Does the following make more sense now?
smtpd_helo_required = yes
smtpd_recipient_restrictions =
reject_non_fqdn_sender,
permit_mynetworks,
permit_sasl_authenticated,
reject_unauth_destination,
reject_unverified_recipient,
reject_unknown_recipient_domain,
reject_non_fqdn_recipient,
reject_unknown_sender_domain,
check_sender_access hash:/etc/postfix/sender_access,
check_recipient_access hash:/etc/postfix/roleaccount_exceptions,
check_helo_access hash:/etc/postfix/helo_checks,
reject_non_fqdn_hostname,
reject_invalid_hostname,
check_sender_mx_access hash:/etc/postfix/bogus_mx,
reject_rbl_client zen.spamhaus.org,
reject_rhsbl_sender dsn.bl.rfc-ignorant.de
smtpd_data_restrictions =
reject_multi_recipient_bounce,
reject_unauth_pipelining
smtpd_relay_restrictions =
permit_mynetworks,
permit_sasl_authenticated,
defer_unauth_destination