Note that Postfix replies with:

>
>     User unknown
>
>     Meaning: the recipient domain matches $mydestination, but the
>     user was not found in $local_recipient_maps.
>
> and that Postfix did not reply with:
>
>     User unknown in virtual alias table
>
>     Meaning: the recipient domain matches $virtual_alias_domains,
>     but the address was not found in $virtual_alias_maps.
>
> This is consistent with your observation that there is no virtual
> alias lookup.
>


Hello Wietse,

Thanks for your suggestions. I set "show_user_unknown_table_name = yes"
on our relays to help with the troubleshooting if this happens again (it
was set to no).
Regarding our configuration, in main.cf, mydestination is set as:

mydestination = $myhostname localhost.$mydomain localhost

where myhostname is the name of the server and mydomain is
a domain that is not handled by any virtual alias domain. So I'm still at a
loss
to figure out why sometimes we get a 550 code when mail is sent to a valid
alias (if sent again it will then go through at random). I was thinking of
running with a higher
debug level on smtpd but wanted to check if this will cause an unacceptable
performance degradation
on production servers (handling tens of thousands of e-mails per hour)? We
are running
RHEL 6.3 on VMWare. Would upgrading to Postfix 2.10.2 be recommended? -- I
looked at the
release notes but am not sure if this would help. Thanks.

cheers,

VM

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