People here might have heard about the work of Prof Emery Berger on the causal 
profiling technology.
Here's a paper presenting Coz, a causal profiler.
https://www.sigops.org/s/conferences/sosp/2015/current/2015-Monterey/printable/090-curtsinger.pdf

They have also release a profiler for Python using the same technology.
It is called Scalene: https://github.com/plasma-umass/scalene

In case Pharo does not have such a profiler, maybe an expert could work on it?

Best,

~Mayuresh

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