On Thu, Jul 21, 2022 at 03:59:30PM -0400, bruno da silva wrote:
>   OS/version: CentOS release 6.9 (Final)

How are these set ?

tail /sys/kernel/mm/ksm/run 
/sys/kernel/mm/transparent_hugepage/{defrag,enabled,khugepaged/defrag} 
/proc/sys/vm/zone_reclaim_mode

I suspect you may be suffering from issues with transparent huge pages.

I suggest to disable KSM and THP, or upgrade to a newer OS.

I've written before about these:
https://www.postgresql.org/message-id/20170524155855.gh31...@telsasoft.com
https://www.postgresql.org/message-id/20190625162338.gf18...@telsasoft.com
https://www.postgresql.org/message-id/20170718180152.ge17...@telsasoft.com
https://www.postgresql.org/message-id/20191004060300.ga11...@telsasoft.com
https://www.postgresql.org/message-id/20200413144254.gs2...@telsasoft.com
https://www.postgresql.org/message-id/20220329182453.ga28...@telsasoft.com

On Thu, Jul 21, 2022 at 04:01:10PM -0400, bruno da silva wrote:
> The issue started a month ago.

Ok .. but how long has the DB been running under this environment ?

-- 
Justin


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