How can Postgres be used and configured as an In-Memory Database?

Does anybody know of thoughts or presentations about this "NoSQL feature" -
beyond e.g. "Perspectives on NoSQL" from Gavin Roy at PGCon 2010)?

Given, say 128 GB memory or more, and (read-mostly) data that fit's into
this, what are the hints to optimize Postgres (postgresql.conf etc.)?

-- Stefan

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