[GENERAL] Full vacuum really slowing query down

[Jason Long]

I have a query that takes 2.5 sec if I run it from a freshly restored 
dump.  If I run a full vacuum on the database it then takes 30 seconds.

Would someone please comment as to why I would see over a 10x slow down 
by only vacuuming the DB?

I am using 8.3.1

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