> Although there are many online tools (e.g., PubChem sketcher) to draw
> structure from SMILES


You can generate 2D depictions as mentioned in the docs:
https://open-babel.readthedocs.io/en/latest/Depiction/depiction.html 
<https://open-babel.readthedocs.io/en/latest/Depiction/depiction.html>

Hope that helps,
-Geoff
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