Hey guys,

i have download the chembl_sdf archive and unpack it.

The resulting sd file from that archive has 2.5 GB.

Now i want to create the fs index datei from that sd file with:

babel -isdf chemble_13.sdf -ofs chembl_13.fs

This command works but if i want to search with an sd file against the fs file 
it doesn't work.

I heard about that the sd file (if you want to create the index file) must be 
smaller then 2 GB. 

What can i do? If i start the search on the sd file it works but it is very 
slow.

With best

Jochen Schreiber



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