In a few days, I will be releasing NONMEM 7.5.1, which should be able to be 
compiled with gfortran/gcc 11 on a MAC with M1 architecture.

Robert J. Bauer, Ph.D.
Senior Director
Pharmacometrics R&D
ICON Early Phase
820 W. Diamond Avenue
Suite 100
Gaithersburg, MD 20878
Office: (215) 616-6428
Mobile: (925) 286-0769
[email protected]<mailto:[email protected]>
www.iconplc.com<http://www.iconplc.com>

From: [email protected] <[email protected]> On Behalf Of 
Mu'taz Jaber
Sent: Thursday, February 3, 2022 12:10 PM
To: Heine, Rob ter <[email protected]>
Cc: [email protected]
Subject: [EXTERNAL] Re: [NMusers] Nonmem 7.5 on MacOS monterey troubleshooting

You can install the previous version of gfortran/gcc binaries from here: 
http://hpc.sourceforge.net/<http://hpc.sourceforge.net/> and build that 
following their instructions. There is a specific version for M1 architecture.
-----------------------------------
Mutaz M. Jaber, PharmD.
PhD Candidate, Pharmacometrics
Experimental and Clinical Pharmacology
University of Minnesota
717 Delaware St SE; Room 468
Minneapolis, MN 55414
Email: [email protected]<mailto:[email protected]>


~ Stay curious


On Thu, Feb 3, 2022 at 2:03 PM Heine, Rob ter 
<[email protected]<mailto:[email protected]>> wrote:
Hi all,

Since the update to MacOS Monterey on my M1 macbook, the installation of nonmem 
does not work anymore.

I have tried reinstalling gfortran and then nonmem. However, it appears that 
nonmem does not compile from GCC version 11, but with homebrew it is not 
possible to install version 10 as instructed in the readme at 
https://nonmem.iconplc.com/#/nonmem750/MACOSX<https://nonmem.iconplc.com/#/nonmem750/MACOSX>
 , since it returns “ gcc@10: The x86_64 architecture is required for this 
software”

Has anyone succeeded in installing nonmem on MacOS Monterey?

Sincerely,
Rob

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