This is likely a specific problem to PDx-Pop, rather than NONMEM.  If you send 
me the example control stream and data set (please do not broadcast on 
nmusers), I may be able to determine a work-around.

Robert J. Bauer, Ph.D.
Vice President, Pharmacometrics R&D
ICON Early Phase
820 W. Diamond Avenue
Suite 100
Gaithersburg, MD 20878
Office: (215) 616-6428
Mobile: (925) 286-0769
robert.ba...@iconplc.com<mailto:robert.ba...@iconplc.com>
www.iconplc.com<http://www.iconplc.com/>

From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On 
Behalf Of soso
Sent: Monday, August 15, 2016 10:22 AM
To: nmusers@globomaxnm.com
Subject: [NMusers] Negative data_PDx run

Hello ALL,

I am using PDx along with NONMEM to conduct a META analysis, but I have 
negative values in my DV column. PDx cannot deal with this and gave me the 
following error message;
“The table file did not get created by NONMEM. It is possible that an error 
occurred in the NONMEM run which was not output to the screen or that the code 
required to create this table was not found in the control file”
PS: when I removed the negative sign from the data in my DV column, PDx was 
able to process the data but it gave a strange results!

Is there any way to deal with these negative data?

Thank you.
<br /><br />
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