Posting: Open systems pharmacology - Principal scientist position at Sanofi. Please contact karim.a...@sanofi.com<mailto:karim.a...@sanofi.com> or apply online at http://www.sanofi.us/l/us/en/layout.jsp?scat=18DAEAAB-BD35-492F-8777-EE9BFE683320, if interested in the position
Job Description: This position is for a modeling scientist in the area of systems pharmacology. The individual will be based in the Department of Translational Informatics, in the Translational Medicine and Early Development organization. The individual will primarily be involved with modeling activities and as appropriate serve as the project team representative. Working with internal and external collaborators will be essential to ensure that modeling meets the strategic needs of the project team. The primary focus will be on modeling efforts which quantitatively integrate pathway biology, physiology and clinical pharmacology, i.e. systems pharmacology. Responsibilities include: * Assess and prioritize the modeling needs and contribute to the strategic modeling work plan for a project * Develop computational systems models working with internal and external collaborators * Communicate with clarity the results of modeling in presentations to key stakeholders * Contribute to translational plans and assessments and study conduct Qualifications: * Formal Education And Experience Required: PhD with a track record of productivity in the areas of systems pharmacology, computational biology or related field, as manifested in publications and presentations. * A minimum of 3 years of experience in biomedical research post-education * Extensive knowledge of biological pathways relevant to disease. Superb skill in communicating both highly technical material as well as the distilled take-home messages. Strong commitment to on-the-job-training. * Modeling and computational experience, Excellent scientific computing and programming skills in a variety of computational tools such as MATLAB, Monolix, NONMEM, Mathematica, R and excellent working knowledge of Linux and Windows environments * Extensive knowledge of biological pathways relevant to disease. * Superb skill in communicating both highly technical material as well as the distilled take-home messages. * Strong commitment to on-the-job-training. * Modeling and computational experience Knowledge And Skills Desirable But Not Essential: * Experience in disease modeling. Expert knowledge in at least one area (e.g. immunology, cardiovascular) highly desirable. Experience in drug discovery/development, especially quantitative aspects such as PK-PD, basic experience in Pharmacometrics or Clinical Pharmacology.
