Be influential. Our Clinical Pharmacology Leads have key roles to play in influencing the discovery and development of drugs. It is fascinating, vital work and you could be part of it. Pfizer is a leader in Model Based Drug Development, and we are expanding its influence in target validation and selection. We have new positions for talented individuals at our Cambridge, MA, USA labs.
Clinical Pharmacology Lead (grades from Manager to Director) at our CVMED or Neuroscience Research Units in Cambridge, MA; In this key role you will serve as the Clinical Pharmacology Lead on multidisciplinary development teams and provide clinical pharmacology expertise and leadership to a project. You will work closely with clinicians and statisticians to create clinical development plans that include assessments of a drug's efficacy, safety, and commercial viability. In collaboration with other quantitative clinical and nonclinical disciplines, the Clinical Pharmacology Lead will integrate PK-PD knowledge from preclinical experiments, clinical results, and meta-analyses of the literature to inform target validation, human administration, and phase 2 study design and analysis. In order to achieve these aims, candidates are responsible for the application and development of innovative analytical methods to integrate knowledge of pharmacokinetics, biopharmaceutics, pharmacodynamics, patient characteristics and disease states to optimize doses, dosage regimens and study designs throughout clinical drug development (including FIH single/multiple doses, proof of concept PK-PD, dose-ranging in patients, drug interactions, special populations, food effects, etc.). Clinical Pharmacology Leads routinely interact with internal leadership, regulatory agencies, and external opinions leaders. We are expected to influence the internal and external environment by advancing quantitative and systems pharmacology and through presentations and publications. The ideal candidates will be proficient communicators with a doctorate degree, strong quantitative skills (e.g. experience in mechanistic modeling/systems pharmacology, literature meta-analyses, population modeling, and clinical trial simulations) and expertise in clinical pharmacology and/or pharmacometrics . We encourage applicants from different disciplines including clinical pharmacology, engineering, biostatistics, medicine, biology, etc. Candidates with significant experience are sought as well as recent graduates. In addition to professional challenge, we offer a culture that supports and encourages ideas, and recognizes individual contribution. To apply please visit the careers pages on www.pfizer.com<http://www.pfizer.com/> and enter the following job opening number: For Clinical Pharmacology in CVMED job opening number: 971402 For Clinical Pharmacology in Neuroscience job opening number: 965962
