The fact that NONMEM7 will not be open source code is very unfortunate, it has not been often, but there have been occasions when by going over the source code I was able to understand aspects of NONMEM programming that were still unclear to me, being able to get a look at the actual algorithms in software had been a major advantage for NONMEM!!!! Alice I Nichols, PhD Sr Director Early Development and Clinical Pharmacology Wyeth Research 500 Arcola Rd Collegeville, PA 19426 tel: 484-865-8741/ fax: 484-865-9075 [email protected]
>>> "Serge Guzy" <[email protected]> 7/3/2009 3:56 AM >>> I do have only one simple question. How many people took advantage from the fact Nonmem was distributed as open source? If we are talking about a very small percentage, is this discussion worthwhile? How many people except bob bauer and may be somebody else I am not aware of are able to follow and understand the cuirrent nonmem code? Serge From: [email protected] To: Ludden, Thomas ; [email protected] Sent: Thu Jul 02 23:46:09 2009 Subject: [NMusers] RE: NONMEM 7 Update Thomas Didn't ICON consider that indeed, this decision might stimulate the divergence of an open-source clade of NONMEM, somewhat like R stemmed out of S-plus? If a small academic group starts to work in that direction, it would certainly be quickly joined by many* Thierry BuclinUniv. Hospital, Lausanne De : [email protected] [mailto:[email protected]] De la part de Ludden, Thomas Envoyé : jeudi, 2. juillet 2009 15:15 À : Eleveld, DJ; [email protected] Cc : Krohn, Anthony Objet : RE: [NMusers] NONMEM 7 Update Dear All:Icon Development Solutions has invested in the further development of NONMEM. By mutual agreement with the University of California at San Francisco, NONMEM 7 is intellectual property belonging to IDS. However, IDS will continue to pay royalties to UCSF. The business plan under which NONMEM 7 was developed calls for the protection of the I.P. involved. In addition, NONMEM 7 contains several updated routines developed and owned by IMSL (Visual Numerics Inc.). Our agreement with IMSL stipulates that we will not distribute their source code. The installer will compile the software but will not allow the unencrypted source code to remain on the users computer. The licensing agreement will also stipulate that any attempt to access the source code will be a violation of the agreement. Some source code will be left unencrypted for various reasons, one being the need for users to change certain values in SIZES and perhaps other resource routines.Tom Thomas M. Ludden Ph.D. Vice-President, Pharmacometrics R&D ICON Development Solutions Tel: + 1 410 696 3040 Mob: + 1 410 258 2411 Fax: + 1 410 480 0776 Email: [email protected]: www.icondevsolutions.com The information contained in this email message may contain confidential or legally privileged information and is intended solely for the use of the named recipient(s). No confidentiality or privilege is waived or lost by any transmission error. If the reader of this message is not the intended recipient, please immediately delete the e-mail and all copies of it from your system, destroy any hard copies of it and notify the sender either by telephone or return e-mail. Any direct or indirect use, disclosure, distribution, printing, or copying of any part of this message is prohibited. Any views expressed in this message are those of the individual sender, except where the message states otherwise and the sender is authorized to state them to be the views of XOMA.
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