Nick,

 

In your code example for the estimation of a 'relative bioavailability'
wouldn't it be necessary to use a logit transformation to keep F1 between 0
and 1? Something like: F1 = 1/(1+exp(BSV_F1))

 

Regards, Andreas.

 

____________________________

 

Andreas Lindauer

 

Department of Clinical Pharmacy

Institute of Pharmacy

University of Bonn

An der Immenburg 4

D-53121 Bonn

 

phone: + 49 228 73 5781

fax:      + 49 228 73 9757

 

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