> X-MShield-Cache-Status: STALE
> 0.004329:0.000000:0.004364:0.000000:0.212526:0.212644

I see according to the timings you hit the 200ms tcp_nopush delay.

Try setting tcp_nopush off;

For more explanation you can read up 
https://forum.nginx.org/read.php?2,280434,280462#msg-280462 

rr

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