> I'd not like to rely on "something you have" and "something else you have" as 
> two separate factors

Using a FIDO key (e.g., sk-ssh-ed25...@openssh.com) is two factors so long as 
user verification is required. This can be enforced on the server by enabling 
the PubkeyAuthOptions verify-required option:

https://man.openbsd.org/sshd_config#PubkeyAuthOptions

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