As far as I know, the only software we have for blind people (and not just people with very poor eye sight) is misc/brltty.
misc/screen also has support in the form of the shm flavor, which hooks to misc/brltty The main issue for this kind of thing is of course testing. This was done over 10 years ago. I have zero idea if this still works, or if there are better tools these days. We also have (had?) a speech synthesis system in audio/festival Unfortunately, this is research code that predates the C++ standard by years, and thus is thoroughly rotten through. I don't think we have any other speech synthesis open source software in the ports tree.