Hi,
Is anybody using an USB-to-serial connection to an ALIX?
Yes i am. We have many Alix 2D13 boards that we use as routers running OpenBSD 5.2 on many sites. I use a USB-to-serial cable to configure them without problem but i've never used anything else than screen or minicom. You could try with these tools...
The default baud rate on alix boards is 38400 but can be changed in cmos setup if you want (pressing S during memory test).
Morgan