> Is there a way to use LyX in Portable Mode without installing MiKTeX?

Yes [1].

> I want to be able to edit TeX files

While LyX uses (La)TeX to produce PDF, it does not use "native" (La)TeX
internally. And importing (La)TeX into LyX is not exactly seamless.

Sincerely,

Wolfgang

[1]  I'm using LyX 2.0 with TeXLive 2010 and SumatraPDF, all portable.

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