Hi,
> LyX: reconfigurando directorio del usuario > File "/Applications/LyX.app/Contents/Resources/configure.py", line 93 > print "Failed to create directory ", dir three blind guesses: 1) have you run the installer-script in the dmg?2) do you have python3 installed? (you should not, at least not as default python) 3) do you have some special characters in your username / path to your home directory?
HTH, Konrad