Michelle Dukich writes:
  
  I am trying to write a grant proposal from a large
  non-profit organization to a foundation.  [...]
  
This may not apply to your own organization and/or the foundation to
which you are applying, but ...

I was the executive director of a foundation (New York Council for the
Humanities) for many years, and before that a senior researcher at
another foundation, and would caution for some foundation submissions
you may do better by `de-tuning' some parameters of LyX and/or LaTeX
so your application will not look too slick or professional.  Some
foundations also react to submissions that are too slick, and may
actually prefer a ragged right edge, double-spacing, and other
manuscript changes that degrade LyX/LaTeX default output to the level
of a glorified typescript.  I run into the same problem with
manuscript submissions to publishers: the elegance and typeset output
quality of LyX/LaTeX is often _not_ desirable in a manuscript and can
be a turn-off to an acquisitions editor.  (The worst extreme is
inexperienced authors who make their manuscript submissions look like
public relations kits!)

Your mileage may vary: you might want to make sure of the foundation
guidelines and submissions preferences before you hunt up or search
out a document class.

(As a trade author of novels and history, my ultimate frustration is
when a publisher insists that I submit a revised manuscript in some
PC-proprietary format like ms-word or in unformatted ascii.  I can
argue all I want; they insist and the elegance and beauty of the
LyX/LaTeX output is instantly lost.  The technical publishing world
pays premiums for camera-ready output; the trade publishing world
still frowns on it.)

-- 

Ronald Florence                 http://members.home.net/18james

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