Jaxer allows you to use javascript and jquery on the server to mess with 
DB/Filesystem/Remote Sites from the client. Calls to
serverside code look exactly like regular javascript.

http://ejohn.org/blog/server-side-javascript-with-jaxer/

http://www.aptana.com/node/336

I do recommend it as a great path from web site to web application development 
as you don't have to learn a whole new toolset, it's pretty much
javascript, DOM, HTML, and a js utility library contained in the Jaxer 
namespace.

I work @ Aptana so my opinion may be biased ;-)


marr.adam wrote:
As with any js, since it runs client-side, you cannot use it to query
a Db, only to call something else that will, such as making a request
to a PHP script or server-side java. PHP is the simplest way. You can
either have the php return the markup to display or maybe have it
return  json object and create the page with js. Either way, jquery or
mootools both have already taken care the complexities, so I would
recommend using them for your requests.

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