Here's my experience with guix-as-a-package-manager, fontconfig and multiple profiles.
If fonts are installed in a profile different than the default one, applications do not pick them up out of the box. I.e. icecat shows characters as squares and you cannot select a cool non standard font in your GTK Emacs. After digging into this matter, I concluded that the culprit is the main config file situated in some-nondefault-guix-profile/etc/fonts/fonts.conf Here's a snippet: ------------------------- <!-- Font directory list --> <dir>/gnu/store/7y3lvk3xf4im8n44337mc6y0ccysvfia-font-dejavu-2.37/share/fonts</dir> <dir>~/.guix-profile/share/fonts</dir> <dir>/run/current-system/profile/share/fonts</dir> <dir prefix="xdg">fonts</dir> <!-- the following element will be removed in the future --> <dir>~/.fonts</dir> --------------------------- Clearly, some-nondefault-guix-profile/share/fonts is not among the list of dirs that are searched for font definitions. I'd call this a bug, but maybe it's by design. Still, shouldn't guix package definitions respect the -p flag to package command? Anyway, the workaround is the following. See this snippet of the same config file, ---------------------------- <!-- Load local system customization file --> <include ignore_missing="yes">conf.d</include> <!-- Font cache directory list --> ----------------------------- This means it includes the conf files in ...profile/etc/conf.d. The README file reveals that 5?-*.conf files are used for additional customisation. This makes 50-user.conf particularly interesting. And, here it is ... ----------------------------- <include ignore_missing="yes" prefix="xdg">fontconfig/conf.d</include> <include ignore_missing="yes" prefix="xdg">fontconfig/fonts.conf</include> <!-- the following elements will be removed in the future --> <include ignore_missing="yes" deprecated="yes">~/.fonts.conf.d</include> <include ignore_missing="yes" deprecated="yes">~/.fonts.conf</include> ----------------------------- Apparently , ~/.config/fontconfig/fonts.conf (xdg prefix being ~/.config) is the place to add some more config After creating ~/.config/fontconfig/fonts.conf with the following content ----------------------------- <?xml version="1.0"?> <!DOCTYPE fontconfig SYSTEM "fonts.dtd"> <!-- /etc/fonts/fonts.conf file to configure system font access --> <fontconfig> <its:rules xmlns:its="http://www.w3.org/2005/11/its" version="1.0"> <its:translateRule translate="no" selector="/fontconfig/*[not(self::description)]"/> </its:rules> <description>Default configuration file</description> <!-- Font directory list --> <dir>~/.guix-pillars/pillar/share/fonts</dir> </fontconfig> ------------------------------ and running fc-cache -rvf the fontconfig-aware programs were able to select fonts from the non-default guix profile. Hope this helps (me again in six monts from now)! T