Hi Philippe,
> Also, is it expected that packages from guix commits dating > from a few years ago will still work in this setting? Thanks! Commits before the introduction of inferiors likely won’t work, unfortunately. For running old versions I recommend writing new package variants instead and including them in a channel. Using inferiors is a good idea when you want to reproduce a Guix environment that somebody else (or your younger self) recorded, but I would not recommend them as a way to make past software variants available. If you are not interested in a particular old state of the world but only care about a particular version of a single piece of software (that may be built with current toolchains and libraries) then package variants are a better idea. For bioinfo package variants also take a look at the guix-bimsb channel: https://github.com/BIMSBbioinfo/guix-bimsb (I should update the README to recommend using channels instead of GUIX_PACKAGE_PATH…) -- Ricardo