Hello Guix,
Just fyi that there is an update to the #52555 patch series that allows more decentralized substitute distribution via protocols such as IPFS or GNUnet: https://issues.guix.gnu.org/52555#46 (I was previously encouraged to post here as some interested people missed the mails to guix-patches). The patch series uses the ERIS encoding (http://purl.org/eris) and implements transport over HTTP (a la RFC 2169) and IPFS. By using ERIS we are quite transport agnostic and could use other things such as GNUnet, NDN, Freenet, CoAP or a bicycle. Cheers, pukkamustard