Quite a few of us here have used and developed against Nix in the past and Nix certainly is a great work and the original inspiration of GNU Guix (and doing things better). When Ludo introduced Guix at FOSDEM in 2014, however, I was convinced to change my ways on the spot - after using Nix (from the early days). This article is from 2008
https://www.linux.com/news/nix-fixes-dependency-hell-all-linux-distributions/ How time flies... In fact, at the University of Tennessee we are building a new exciting HPC around GNU Guix right now which will also run containers and will give researchers a lot of freedom. We'll write it up when the beast is running. Pj.