Go 100 off-heap.

You may use other in-memory database for data, running on a same machine. I 
recomend Tarantool: http://tarantool.org - it is capable to handle hundreds of 
thousands (up to million) requests per second on just one CPU core. If you need 
more, then you may consider sharding. If you need no persistency, you may 
disable logging.

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