Felipe Villanelo wrote:
Hi gmxs,
I'm trying to compute a aproximated D G of binding between two proteins
using a termodynamic cycle, and the D Gsol calculated with g_sas (from
10 ns dynamics for every situation)
But I had read here, that the value this way calculated is useless.... why?
First you have to check the literature. This calculation is based on a
paper more than 20 years old, and the main feature of this calculation
is it's simplicity. Second you have to verify that the calculation is
done correctly...
Waiting for answer
-----
Felipe Villanelo Lizana
Biochemist
Laboratorio de Biología Estructural y Molecular
Universidad de Chile
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