Torsten Stauder wrote:
So the native and the insert structures are known....
Any suggestions how to model such a ITD-sequence into a wild type
receptor?
... so what's the problem?
I wouldn't ask if I'd know how to do that....
Well if you have structures, you can cut and paste them together in any
number of molecule-building programs. If you don't have structures then
you have an awkward problem - you now either want to do an homology
model using some other software, and/or want to guess something vaguely
reasonable and do an MD simulation and see what you find out.
Mark
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