(I'm asking this question only because I'm curious about the problem I'm about to describe. I've already worked around it.)
I updated the kernel in my gentoo virtualbox guest machine to 4.1.8 and got a kernel panic after rebooting the guest. (The panic was in the guest machine, not the host machine. Has anyone noticed how ambiguous our English language is?) Anyway, I rebooted the guest machine with vmlinuz.old (3.18.21) and then updated the guest to vanilla-sources-4.2.3 with no problems. (I omit several hours of confused reconfiguring/recompiling/rebooting because you really don't want to hear about them.) So, what is different or strange about kernel 4.1.8? Anyone have any problems with it on real hardware, or in other virtual environments like qemu, vmware, xen, etc?