Hi, If anyone encounters issues with building gtk-doc-1.18 (needed for gimp "doc" USE flag, amongst others) you need to have the "python" flag enabled for the libxml2 package in order to build gtk-doc (the gtk-doc fails to build due to not finding libxml2 module [which I assume is a python one]). I guess this is related to the "python" USE flag removal in the profiles...
Best regards Peter K