https://gcc.gnu.org/bugzilla/show_bug.cgi?id=111907
--- Comment #4 from Haochen Jiang <haochen.jiang at intel dot com> --- I guess it is caused by "*andnot<mode>3", not confirmed yet. The isa for the last constraint changed to avx512f_512, which will make the pattern disabled under -mavx512f -mno-evex512. Let me find a solution on that.