https://gcc.gnu.org/bugzilla/show_bug.cgi?id=89794
--- Comment #6 from Richard Earnshaw <rearnsha at gcc dot gnu.org> --- There seems to be more to this than initially thought. Another insn is in play. (insn 12 10 14 2 (set (reg:SI 129) (bswap:SI (subreg:SI (reg:DI 127 [ i ]) 4))) "/tmp/test3.c":10:7 331 {*arm_rev} (expr_list:REG_DEAD (reg:DI 127 [ i ]) (nil))) Which uses the value loaded by the pre-modify instruction. Combine manages to combine (and simplify insns 10 and 12, but the simplification is to (set (reg:SI 129) (const_int 0)) and we've lost the pre-inc entirely.