Well, FWIW, posts like this help me. I'm particularly susceptible to 
over-simplification, especially when it comes in an optimistic package. I need 
all 3 of realism, pessimism, and cynicism to keep my episodic forgetting in 
check. In particular, here, your remembering:

• the complicated calculus in trusting agencies under cronyism,
• all the social chaos (BLM, right-wing rallies, etc.) coinciding with 
COVID-19, and
• that each attempt at expression should be as authentic and error-correcting 
as possible

I need continual (not periodic, not discrete) reminders of that last one. 
Thanks.

On 5/6/21 3:38 PM, David Eric Smith wrote:
> Pieter, there is a good conversation to have here, but these bastards who 
> seem committed to doing _everything_ in bad faith irritate me to the point 
> where I spend time writing FRIAM posts instead of doing anything that will 
> _ever_ benefit anyone or accomplish anything.  
> 
> Yes, the mRNA platform is great, and should be a geme-changer.  Let’s pursue 
> that topic.  I’m fully with you on that.
> 
> And?
> 
> Oh, human challenge trials are an “innovative technique”.  They also 
> explicitly violate the Hippocratic oath.  Do we fail to do them for no 
> particular reason, or has someone thought about whether the Hippocratic oath 
> is an important consideration?  Dunno, hmmmm.  How would one decide?
> 
> Oh, public health people admonished Americans away from buying medical masks 
> early on.  Clearly just because those bureaucrats are so dead set against 
> efficiency.  We haven’t had that conversation ad nauseam on this channel 
> already?   We know why they did it; they are communicating to Americans, 
> which is like communicating to a troupe of Tasmanian devils surrounding a 
> roadkill.  They know their words have consequences, and they feel the weight 
> of that responsibility.  Then, sometimes they also make mistakes.  Do we 
> criticize to correct, or exploit to destroy?
> 
> And, just by the bye of things not mentioned.  Let’s do a ballpark of what 
> the best-case scenario might have been with very proactive response and 
> people really trying to work together, like maybe some events in US society 
> in WWII.  Instead of having spent maybe USD5Tn by the end of the trump term, 
> with — what was it at the time — something like 450k people dead, I could 
> imagine that with a scaled-up S. Korea like response, the economic support 
> could have been maybe USD 1Tn to 1.5Tn to achieve a similar backstop, and 
> maybe 100k people dead.  That would have been _really hard_ to pull off, but 
> it is the kind of hard that good countries aspire to and sometimes achieve. 
> And the fact that _all_ that didn’t happen is clearly to the fault of some 
> public health people who didn’t know early how much transmission was fomites 
> and how much respiratory droplets?  Or trying to redirect masks to hospitals? 
>  The public health people were _against_ testing?  I believe that last claim 
> is
> flatly false, and overwhelmingly documented to be so.  There was nothing else 
> going on at the time?  Hmm, can’t recall.  Or since?  Or still, even worse?  
> How would one tell?  And Americans have a great record of really being 
> supportive of each other, and using great reasoning based on all the best 
> evidence, but were just thwarted again and again by the public health 
> officials and agencies?  
> 
> And the vaccines were developed so rapidly, this time only because the 
> agencies removed obstacles that they could have removed any time.  Well, for 
> the adenovirus vaccines (a largely established technology)  there is a claim 
> to that effect that can be made fairly.  But of course the article puts up 
> the mRNA vaccines as evidence of how, because the agencies got out of the way 
> (is implied), BioNTech and Moderna had vaccines in a few days.  That is 
> deliberate BS, and I doubt the writer is such an idiot that he doesn’t know 
> it.  (cf. the very useful article in NYT a couple of weeks ago on Kariko and 
> a little about the history of mRNA update and expression research.)  They 
> were done in a few days because of 30 years of work, much of it publicly 
> funded, that was waiting in the wings, and had been postponed earlier, and 
> only pushed through now, only because there hadn’t been a disease structure 
> that enabled the (non-human-challenge) trial at a price the companies were 
> willing to
> pay.  The disinformation on that simple matter of fact has been wonderfully 
> employed by those who will now ensure that we have an endemic, no longer just 
> a pandemic.
> 
> And now there is a fight on about suspending patent limits on vaccine 
> production to open to more operators, and the companies argue that it 
> wouldn’t make any difference because it is current capacity saturation that 
> limits us (Jon’s DW news articles yesterday, which the Canadians say is false 
> even now), deliberately bypassing the obvious intent of the suspension that 
> capacity can be built by more actors in parallel, going forward from now.  
> The company objection is that it would not be capacity _they own_, cf my rant 
> from yesterday.  But sure, now that the technology _exists_, clearly everyone 
> will be fine.  I find that foreshortening of the conversation harmful, 
> because it is again anti-empirical.  We are not distributing the technology 
> we have well enough to evade an endemic — the needed and productive 
> conversation is in large part WHY that is occurring, and what we want to 
> change.  These guys will tie themselves in any knot to distract from a real 
> version of that discussion.
> 
> So I don’t object to all the good points you raise about mRNA vaccines and 
> their potential.  I feel obliged to notice, however, the specific strategy by 
> this klatch of writers, of using the techno-points to obstruct the 
> conversation about human cooperation, which is immediately actionable, and 
> responsible for a large part of the shortfall.  Because the empirical 
> discussion is in large part a discussion about the restraint of POWER.  They 
> live to prevent that discussion, and they will take us all down with them if 
> they succeed.
> 
> There is a thing we do, that they exploit.  If they include a few statements 
> that aren’t false in an overall framework that is deliberately distorted, we 
> all bend over backward to grant them standing because a few things they say 
> overlap with the truth.  Maybe at first, a little.  But conversations have a 
> pragmatics and it is relevant.
> 
> So, onward…
> 
> Eric
> 
> 
> 
>> On May 7, 2021, at 6:02 AM, Pieter Steenekamp <[email protected] 
>> <mailto:[email protected]>> wrote:
>>
>> I know I run the risk of responses like "it's Pollyanna, oh sorry I mean 
>> Pieter, again", but I'll take the risk and share the link with the 
>> speculation about technological progress with mRNA vaccines that will end 
>> pandemics like covid.
>> https://reason.com/video/2021/05/06/why-covid-19-may-be-the-last-pandemic/ 
>> <https://reason.com/video/2021/05/06/why-covid-19-may-be-the-last-pandemic/> 
>>


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