External Email - Use Caution
Do you have a Freesurfer page I can read up on those hybrid ways just to see
whether that could be an option?
Also, although its a binary, you would recommend against have sex be a
continuous measurement like age, due to the design of how the contrasts are
determined? I.e continuous measurements aren't treated like integers
Victor Zeng
Beth Israel Deaconess Medical Center
Keshavan Lab
--
________________________________
From: freesurfer-boun...@nmr.mgh.harvard.edu
<freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Douglas N. Greve
<dgr...@mgh.harvard.edu>
Sent: Sunday, February 13, 2022 12:24 PM
To: freesurfer@nmr.mgh.harvard.edu <freesurfer@nmr.mgh.harvard.edu>
Subject: [External] Re: [Freesurfer] classes for GLM analysis
It is probably not going to work very well if you have some classes that only
have one member. You can eliminate members of classes that only have a few
members. If you really need to have those cases, there are hybrid ways to
analyze the data (but you can't use an FSGD at that point)
On 2/6/2022 10:41 PM, Zeng, Victor (BIDMC - Keshavan - Psychiatry) wrote:
External Email - Use Caution
Hi all,
I am doing an analysis and generating the FSGD. I understand sex and race are
classes in this context, but something I was also hoping to regress out is the
effects of scanner/sequences. We have a large participant size, so we have
around 10+ scanner/sequences, which makes for a large amount of classes
combinations, with some having just 1 (if not zero) fitting into a class.
Would you proceed with this nonetheless? If not, should scanner/sequence be
something that we consider? Should we find some other way to adjust site (I
don't think we can z-score...). Or can we consider site/scanner as a continuous
variable
Victor Zeng
Beth Israel Deaconess Medical Center
Keshavan Lab
--
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