I just wanted to follow up on this - based on the output I sent
previously, they seem to have the same resolution (unless I've missed
something). They do have different orientations. Could this be an
issue, or can gmlfit handle that? I'm also really stumped as to why
I appear to be getting good F.nii.gz files, but bad sig.nii.gz files.
------------------------------------------------------------------------
*From:* Pedersen, Walker Scott <wpeder...@mgh.harvard.edu>
<mailto:wpeder...@mgh.harvard.edu>
*Sent:* Thursday, September 23, 2021 1:40 PM
*To:* freesurfer@nmr.mgh.harvard.edu
<mailto:freesurfer@nmr.mgh.harvard.edu>
<freesurfer@nmr.mgh.harvard.edu> <mailto:freesurfer@nmr.mgh.harvard.edu>
*Subject:* Re: [Freesurfer] glmfit sig file all zeros
Here is what I get for the mask:
______________________________________________________
Volume information for
/autofs/cluster/neuromod/NIFTI/OCD_NM/derivatives/fsfast/rois/recall/lIFG_surf_rad10.nii.gz
type: nii
dimensions: 163842 x 1 x 1
voxel sizes: 1.000000, 1.000000, 1.000000
type: FLOAT (3)
fov: 163842.000
dof: 1
xstart: -81921.0, xend: 81921.0
ystart: -0.5, yend: 0.5
zstart: -0.5, zend: 0.5
TR: 0.00 msec, TE: 0.00 msec, TI: 0.00 msec, flip angle:
0.00 degrees
nframes: 1
PhEncDir: UNKNOWN
FieldStrength: 0.000000
ras xform present
xform info: x_r = -1.0000, y_r = -0.0000, z_r = -0.0000, c_r =
-68268.5000
: x_a = -0.0000, y_a = 1.0000, z_a = -0.0000, c_a =
-17.0000
: x_s = 0.0000, y_s = 0.0000, z_s = 1.0000, c_s =
16.5000
Orientation : LAS
Primary Slice Direction: axial
voxel to ras transform:
-1.0000 -0.0000 -0.0000 13652.5000
-0.0000 1.0000 -0.0000 -17.5000
0.0000 0.0000 1.0000 16.0000
0.0000 0.0000 0.0000 1.0000
voxel-to-ras determinant -1
ras to voxel transform:
-1.0000 -0.0000 -0.0000 13652.5000
-0.0000 1.0000 -0.0000 17.5000
-0.0000 -0.0000 1.0000 -16.0000
-0.0000 -0.0000 -0.0000 1.0000
______________________________________________________
And here is what I get for the input ces file:
______________________________________________________
Volume information for
/autofs/cluster/neuromod/NIFTI/OCD_NM/derivatives/fsfast/concat/postMpre/recall/recall.sm5.lh/lCS+E_m_lCS-atCS+E/ces.nii.gz
type: nii
dimensions: 163842 x 1 x 1 x 17
voxel sizes: 1.000000, 1.000000, 1.000000
type: FLOAT (3)
fov: 163842.000
dof: 1
xstart: -81921.0, xend: 81921.0
ystart: -0.5, yend: 0.5
zstart: -0.5, zend: 0.5
TR: 2560.00 msec, TE: 0.00 msec, TI: 0.00 msec, flip
angle: 0.00 degrees
nframes: 17
PhEncDir: UNKNOWN
FieldStrength: 0.000000
ras xform present
xform info: x_r = -1.0000, y_r = 0.0000, z_r = 0.0000, c_r =
-68267.5000
: x_a = 0.0000, y_a = 0.0000, z_a = 1.0000, c_a =
-2.5000
: x_s = 0.0000, y_s = -1.0000, z_s = 0.0000, c_s =
0.0000
Orientation : LIA
Primary Slice Direction: coronal
voxel to ras transform:
-1.0000 0.0000 0.0000 13653.5000
0.0000 0.0000 1.0000 -3.0000
0.0000 -1.0000 0.0000 0.5000
0.0000 0.0000 0.0000 1.0000
voxel-to-ras determinant -1
ras to voxel transform:
-1.0000 -0.0000 -0.0000 13653.5000
-0.0000 -0.0000 -1.0000 0.5000
-0.0000 1.0000 -0.0000 3.0000
-0.0000 -0.0000 -0.0000 1.0000
------------------------------------------------------------------------
*From:* freesurfer-boun...@nmr.mgh.harvard.edu
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu>
<freesurfer-boun...@nmr.mgh.harvard.edu>
<mailto:freesurfer-boun...@nmr.mgh.harvard.edu> on behalf of Douglas
N. Greve <dgr...@mgh.harvard.edu> <mailto:dgr...@mgh.harvard.edu>
*Sent:* Thursday, September 23, 2021 10:19 AM
*To:* freesurfer@nmr.mgh.harvard.edu
<mailto:freesurfer@nmr.mgh.harvard.edu>
<freesurfer@nmr.mgh.harvard.edu> <mailto:freesurfer@nmr.mgh.harvard.edu>
*Subject:* Re: [Freesurfer] glmfit sig file all zeros
It looks like the mask is the wrong size. What is the dimension of
/autofs/cluster/neuromod/NIFTI/OCD_N
M/derivatives/fsfast/rois/recall/lIFG_surf_rad10.nii.gz
you can check with mri_info
On 9/17/2021 8:32 PM, Pedersen, Walker Scott wrote:
Hi,
I am running glmfit on some functional data (using ces.nii.gz
surface files as input) using ROIs and the --mask argument, that I
plan to later submit to glmfit-sim for small volume correction. I
have some rois that are subcortical and some that are surfaces. For
the glmfit run within the surface ROIs the output sig.nii.gz files
all voxels have a value of zero. However, this is not the case for
the F.nii.gz and z.nii.gz files output by the same glmfit command -
they have non-zero voxels. This issue only occurs for the surface
ROIs, when I run glmfit in subcortical ROIs the sig.nii.gz files
look normal.
The surface ROIs were created by using afnis 3dundump to create 10mm
spheres from MNI coordinates. I then ran the MNI template through
freesurfer, and used the regheader from this to run mri_vol2surf to
put the spherical ROIs into fsaverage space. I am able to view the
resulting surface ROIs projected onto the fsaverage surface in
freeview, and have checked that my ces.nii.gz function files can
also be overlayed onto the same fsaverage template in freeview.
The output of one of the glmfit commands in question is below.
thanks!
WARNING: gdfReadV1: no variables on 'Variables' line found
Reading source surface
/autofs/cluster/neuromod/programs/freesurfer_7.1.1/freesurfer/subjects/fsaverage/surf/lh.white
gdfRead(): reading
/autofs/space/uriline_003/users/projects/OCD_NM/walker_pedersen/data/image/main/recall/inputFiles/
/fsgd.txt
INFO: gd2mtx_method is dods
Number of vertices 163842
Number of faces 327680
Total area 65417.000000
AvgVtxArea 0.399269
AvgVtxDist 0.721953
StdVtxDist 0.195472
7.1.1
cwd /autofs/cluster/neuromod/NIFTI/OCD_NM/derivatives/fsfast
cmdline mri_glmfit --glmdir
/autofs/space/uriline_003/users/projects/OCD_NM/walker_pedersen/data/image/main/recall/lC
S+E_m_lCS-atCS+E/outputFiles/lIFG/ --y
/autofs/cluster/neuromod/NIFTI/OCD_NM/derivatives/fsfast/concat/postMpre/recal
l//recall.sm5.lh/lCS+E_m_lCS-atCS+E/ces.nii.gz --surf fsaverage lh
--fsgd /autofs/space/uriline_003/users/projects/OC
D_NM/walker_pedersen/data/image/main/recall/inputFiles//fsgd.txt --C
/autofs/space/uriline_003/users/projects/OCD_NM/
walker_pedersen/data/image/main/recall/inputFiles//groupDiff.mtx
--nii.gz --mask /autofs/cluster/neuromod/NIFTI/OCD_N
M/derivatives/fsfast/rois/recall/lIFG_surf_rad10.nii.gz --eres-save
sysname Linux
hostname r440-28.nmr.mgh.harvard.edu
machine x86_64
user wsp6
FixVertexAreaFlag = 1
UseMaskWithSmoothing 1
OneSampleGroupMean 0
y
/autofs/cluster/neuromod/NIFTI/OCD_NM/derivatives/fsfast/concat/postMpre/recall/recall.sm5.lh/lCS+E_m_lCS-atCS+E
/ces.nii.gz
logyflag 0
usedti 0
FSGD
/autofs/space/uriline_003/users/projects/OCD_NM/walker_pedersen/data/image/main/recall/inputFiles//fsgd.txt
mask
/autofs/cluster/neuromod/NIFTI/OCD_NM/derivatives/fsfast/rois/recall/lIFG_surf_rad10.nii.gz
maskinv 0
glmdir
/autofs/space/uriline_003/users/projects/OCD_NM/walker_pedersen/data/image/main/recall/lCS+E_m_lCS-atCS+E/outp
utFiles/lIFG/
IllCondOK 0
ReScaleX 1
DoFFx 0
Creating output directory
/autofs/space/uriline_003/users/projects/OCD_NM/walker_pedersen/data/image/main/recall/lCS+
E_m_lCS-atCS+E/outputFiles/lIFG/
Loading y from
/autofs/cluster/neuromod/NIFTI/OCD_NM/derivatives/fsfast/concat/postMpre/recall/recall.sm5.lh/lCS+E_m_
lCS-atCS+E/ces.nii.gz
... done reading.
INFO: gd2mtx_method is dods
Saving design matrix to
/autofs/space/uriline_003/users/projects/OCD_NM/walker_pedersen/data/image/main/recall/lCS+E_
m_lCS-atCS+E/outputFiles/lIFG//Xg.dat
Computing normalized matrix
Normalized matrix condition is 1
Matrix condition is 1.125
Pruning voxels by thr: 1.175494e-38
Found 512 voxels in mask
Saving mask to
/autofs/space/uriline_003/users/projects/OCD_NM/walker_pedersen/data/image/main/recall/lCS+E_m_lCS-atC
S+E/outputFiles/lIFG//mask.nii.gz
Reshaping mriglm->mask...
search space = 222.026773
DOF = 15
Starting fit and test
Fit completed in 0.0002 minutes
Computing spatial AR1 on surface
Residual: ar1mn=0.987586, ar1std=0.043927, gstd=3.620916, fwhm=8.526606
Writing results
groupDiff
MRImask(): AllowDiffGeom = 1
INFO: MRImask() using MRImaskDifferentGeometry()
maxvox sig=-0 F=4.36504 at index 391 0 0 seed=1632900996
mri_glmfit done
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