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Dear Douglas

I did normalize ICV values. This is something else I guess.

With regards
Vittal



On Tue, Jan 21, 2020 at 6:09 PM vittal korann <vittalkor...@gmail.com>
wrote:

> Dear FreeSurfer experts
>
> I ran QDEC and got the following error.
>
> Design matrix ------------------
>  1.00000   1.04000  -1.38574   2.00000   29.00000   19.00000;
>  1.00000   1.04000  -0.55066   2.00000   35.00000   19.00000;
>  1.00000   1.03000   2.31721   2.00000   23.00000   14.00000;
>  1.00000   1.03000  -0.22919   2.00000   23.00000   16.00000;
>  1.00000   1.03000  -2.69688  -2.00000   28.00000   19.00000;
>  1.00000   1.01000   0.84981  -2.00000   22.00000   19.00000;
>  1.00000   1.01000   0.43845   2.00000   36.00000   21.00000;
>  1.00000   1.06000   1.32888   2.00000   28.00000   17.00000;
>  1.00000   1.02000   0.52292   2.00000   34.00000   22.00000;
>  1.00000   1.02000   0.18104   2.00000   32.00000   17.00000;
>  1.00000   1.03000  -0.33783  -2.00000   32.00000   22.00000;
>  1.00000   1.04000   0.65805   2.00000   30.00000   17.00000;
>  1.00000   1.03000   1.21888   2.00000   37.00000   10.00000;
>  1.00000   1.02000   2.11598   2.00000   29.00000   10.00000;
>  1.00000   1.02000  -0.02853   2.00000   27.00000   16.00000;
>  1.00000   1.04000   0.21777   2.00000   36.00000   16.00000;
>  1.00000   1.01000   0.30821   2.00000   29.00000   15.00000;
>  1.00000   1.03000  -0.69389   2.00000   30.00000   12.00000;
>  1.00000   1.04000   0.44792   2.00000   23.00000   15.00000;
>  1.00000   1.03000   0.15876   2.00000   28.00000   15.00000;
>  1.00000   1.02000  -1.05796   2.00000   36.00000   10.00000;
>  1.00000   1.05000  -1.51878   2.00000   32.00000   15.00000;
>  1.00000   1.03000  -0.91870  -2.00000   30.00000   15.00000;
> --------------------------------
> ERROR: matrix is ill-conditioned or badly scaled, condno = 68200
> --------------------------------
> Possible problem with experimental design:
> Check for duplicate entries and/or lack of range of
> continuous variables within a class.
> If you seek help with this problem, make sure to send:
>   1. Your command line:
>     mri_glmfit.bin --y /usr/local/freesurfer/subjects/qdec/Untitled/y.mgh
> --fsgd /usr/local/freesurfer/subjects/qdec/Untitled/qdec.fsgd dods --glmdir
> /usr/local/freesurfer/subjects/qdec/Untitled --surf fsaverage lh --label
> /usr/local/freesurfer/subjects/fsaverage/label/lh.aparc.label --C
> /usr/local/freesurfer/subjects/qdec/Untitled/contrasts/lh-Avg-Intercept-thickness.mat
> --C
> /usr/local/freesurfer/subjects/qdec/Untitled/contrasts/lh-Avg-thickness-Vein_Avg_tort-Cor.mat
>
>   2. The FSGD file (if using one)
>   3. And the design matrix above
> Attempting to diagnose further
> SumSq: Min=4.795832 (col 1), Max=145.206757 (col 5)
>  The scale is much different between columns 1 and 5, you may want to
>  normalize by subtracting the mean and dividing by the standard deviation.
>
> Any help would be appreciated!
>
> With regards
> Korann
>
>
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