Try normalizing your continuous variables (ie, subtract the mean and divide by the stddev)
On 07/28/2016 06:06 AM, Mahtab Farahbakhsh wrote: > Dear FreeSurfer, > > I am trying to compare my subjects to the healthy group, but when I > put the matrix into qdec, I get the following error: > > Normalized matrix condition is 1e+08 > Design matrix ------------------ > 1.000 0.000 0.000 0.000 68.000 0.000 0.000 0.000; > 0.000 0.000 1.000 0.000 0.000 0.000 66.000 0.000; > 1.000 0.000 0.000 0.000 40.000 0.000 0.000 0.000; > 0.000 0.000 1.000 0.000 0.000 0.000 35.000 0.000; > 1.000 0.000 0.000 0.000 72.000 0.000 0.000 0.000; > 0.000 0.000 1.000 0.000 0.000 0.000 71.000 0.000; > 1.000 0.000 0.000 0.000 22.000 0.000 0.000 0.000; > 0.000 0.000 1.000 0.000 0.000 0.000 22.000 0.000; > 0.000 1.000 0.000 0.000 0.000 20.000 0.000 0.000; > 0.000 0.000 0.000 1.000 0.000 0.000 0.000 20.000; > -------------------------------- > ERROR: matrix is ill-conditioned or badly scaled, condno = 1e+08 > > > 1. Your command line: > mri_glmfit --y > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/y.mgh > > --fsgd > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/qdec.fsgd > > dods --glmdir > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled > --surf fsaverage lh --label > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/fsaverage/label/lh.aparc.label > > --C > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Avg-Intercept-thickness.mat > > --C > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Avg-thickness-age-Cor.mat > > --C > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Diff-Male-Female-Intercept-thickness.mat > > --C > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Diff-Male-Female-Cor-thickness-age.mat > > --C > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Diff-spelling-healthy-Intercept-thickness.mat > > --C > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-Diff-spelling-healthy-Cor-thickness-age.mat > > --C > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-X-gender2-diagnosis_spelling-Intercept-thickness.mat > > --C > /Applications/freesurfer/experimental_data/FAM_TG/DICOM_DATA/qdec/Untitled/contrasts/lh-X-gender2-diagnosis_spelling-Cor-thickness-age.mat > > > > > > the table file is also attached to the mail. > > Would you please kindly guide me with this? > > Best Regards, > Mahtab. > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2 www.nmr.mgh.harvard.edu/facility/filedrop/index.html Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/ _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.