Hi Kim

we of course always strive to make things more accurate, but in the end 
it will depend on the details of your acquisition and such. I don't think 
I have a better answer than that, other than to say look at the 
segmentations and see if you think they are more accurate in one case 
than the other.

sorry
Bruce
On Sun, 23 Mar 2014, jh kim wrote:

> Dear Prof. Fischl
> Thanks for the prompt response.
> 
> The more specific reason of my query is that there was a difference in
> statistical significance between two FS versions.
> For example, the result of group comparison of left thalamic volumes (ANCOVA
> controlling for age and eICV) is statistically significant (p = 0.04) when
> using FS 5.1, whereas the result is no longer significant at all (p = 0.28)
> in case of FS 5.3.
> I'm a little confused about this discrepancy.
> Which result should I trust?
> 
> Thank you in advance for your comments.
> 
> Kim
> 
> 
> 2014-03-23 2:59 GMT+09:00 Bruce Fischl <fis...@nmr.mgh.harvard.edu>:
>       Hi Kim
>
>       there are probably lots of little reasons for the differences.
>       This is
>       always true for different versions, and the reason we never mix
>       versions
>
>       cheers
>       Bruce
>       On
>       Sun, 23 Mar 2014, jh kim wrote:
>
>       > Dear FS lists
>       > When I measured subcortical GM volumes in the same subjects by
>       using both
>       > version 5.1 and 5.3, I have observed a considerable difference
>       in volumes
>       > between the two versions.
>       > For instance, please see the left thalamic volumes below.
>       > I cannot figure out why there is much difference between the
>       versions.
>       > Which result is more reliable?
>       >
>       > Left-Thalamus-Proper_5.3
>       > Left-Thalamus-Proper_5.1
>       > 10313
>       > 9757
>       > 8924.8
>       > 7746
>       > 9834.8
>       > 8287
>       > 7935.2
>       > 7034
>       > 8764.1
>       > 7747
>       > 9411.8
>       > 8037
>       > 7636.7
>       > 8051
>       > 9334.7
>       > 8255
>       > 10024.3
>       > 8171
>       > 8757.7
>       > 6900
>       > 9540.9
>       > 8316
>       > 9294.4
>       > 8369
>       > 8091
>       > 7366
>       > 9103.7
>       > 7818
>       > 9310.2
>       > 7974
>       > 7583
>       > 6872
>       > 9838.9
>       > 8911
>       > 8829.6
>       > 8004
>       > 9094.8
>       > 6973
>       > 9492.3
>       > 8922
>       > 8821.6
>       > 7691
>       > 7971.6
>       > 7376
>       > 9901.2
>       > 8936
>       > 9773.9
>       > 8855
>       > 9283.7
>       > 7615
>       > 8801.6
>       > 7690
>       > 8505.1
>       > 7325
>       > 8981
>       > 7258
>       > 9644.7
>       > 8860
>       > 9104.2
>       > 8298
>       > 8494.8
>       > 7402
>       > 9024.9
>       > 7721
>       > 8117.8
>       > 7226
>       > 8001.8
>       > 7548
>       > 8392.3
>       > 7668
>       > 8606.6
>       > 8173
>       > 9126.7
>       > 7595
>       > 8093
>       > 7885
>       > 8317.7
>       > 7157
>       > 10556
>       > 9307
>       > 8669.6
>       > 8374
>       > 8034.7
>       > 7338
>       > 8148.5
>       > 7276
>       > 9048.1
>       > 8064
>       > 8160.1
>       > 7014
>       > 8747.9
>       > 7894
>       > 8329.9
>       > 6866
>       > 8415.8
>       > 8189
>       > 9246.9
>       > 8256
>       > 8194.1
>       > 7183
>       > 9629.2
>       > 9579
>       > 7688.2
>       > 6398
>       > 8349.2
>       > 8238
>       > 8366.2
>       > 7348
>       > 8436.5
>       > 7616
>       > 8372.3
>       > 6977
>       > 9396.4
>       > 7589
>       > 9327.5
>       > 7684
>       > 10001.8
>       > 8627
>       > 9762.4
>       > 9228
>       > 8841
>       > 8532
>       > 8342.4
>       > 8024
>       > 8645.7
>       > 7725
>       >
>       > Any comment would be appreciated.
>       > Thank you.
>       >
>       > Kim
>       >
>       >
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