Thank you Bruce!
Good! So, at least it doesn't seem an impossible thing to achieve!!
Best,
Markus


2014-03-12 13:21 GMT+01:00 Bruce Fischl <fis...@nmr.mgh.harvard.edu>:

> Hi Markus
>
> there is no way to know until you try it. There are many possible sources
> of variance depending on e.g. how uniformly they are calibrated, but you
> have to try and see.
>
> cheers
> Bruce
>
> On Wed, 12 Mar 2014, Markus Gschwind wrote:
>
>  Dear all,
>> I am planning to create a "local cortical thickness normal template" in
>> order to test single patients against it.
>>
>> For that purpose I was planning to use 50-100 MPRAGE scans of healthy
>> subjects (balanced for age range and sex).
>>
>> My question is, if I should worry about the scanner where the data comes
>> form. We have three Siemens Trios, the MPRAGES are more or less the same
>> protocols.
>>
>> - when the created template with standart deviation map comes from all
>> three
>> scanners, can I test patients coming from all three scanners? Will it
>> reduce
>> sensitivity?
>>
>> - when the created template comes from only one scanner, it is clear that
>> I
>> will not be able to compare patients coming from another scanner against
>> it.
>>
>> Thank you!
>>
>> Markus
>>
>>
>>
>>
>>
>
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