Linda, try demeaning your covariates and see if the problem goes away
doug

On 01/30/2014 03:24 PM, Linda Zhang wrote:
> Dear all,
>
> Whilst running mri_glmfit, the following error occurred:
>
> ERROR: matrix is ill-conditioned or badly scaled, condno = 12375.1
>
> I've attached the design matrix, the fsgd file, and one of the
> contrast matrices as an example.  The command line was:
>
> mri_glmfit --glmdir lh.all.thickness.glmdir --y lh.thickness.10.mgh
> --fsgd all.fsgd dods --C allavovsallcvo.mtx --C avovscvo.mtx --C
> mavovsavo.mtx --C mavovsmcvo.mtx --C mcvovscvo.mtx --surf fsaverage lh
> --cortex
>
> What should I change?
>
> Cheers,
> Linda
>
>
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-- 
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